Efficacy and Safety of Glucosamine Versus Ibuprofen in Patients with Knee Osteoarthritis

Glucosamine Vs. Ibuprofen in Knee Osteoarthritis

Efficacy and Safety of Glucosamine Sulfate Versus Ibuprofen in Patients with Knee Osteoarthritis
Article Summary:
A study was done in China involving people with osteoarthritis of the knee to determine the effectiveness of glucosamine versus ibuprofen. Patients were separated into two groups and administered either 1500 mg of glucosamine or 1200 mg of ibuprofen. Patients’ pain were recorded at 2 weeks and 4 weeks of treatment and also 2 weeks after the treatment ended. The mobility of the knee and swelling of the knee were also recorded at these times. The patients who received the glucosamine treatments reported less pain than those taking ibuprofen, as well as better mobility and less swelling. Those taking the glucosamine also reported less adverse side effects than those taking ibuprofen. The glucosamine is considered an effective treatment for arthritis, and should be considered an alternative to NSAIDs and ibuprofen, and also has very few side effects.

Qiu GX. Gao SN. Giacovelli G. Rovati L. Setnikar I.

Peking Union Medical College Hospital, The People’s Republic of China.

Country of Publication:

Arzneimittel-Forschung. 48(5):469-74, 1998 May.

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