Efficacy and Safety of Intramuscular Glucosamine in Osteoarthritis of the Knee

Glucosamine Safety in Knee Osteoarthritis

Efficacy and Safety of Intramuscular Glucosamine Sulfate in Osteoarthritis of the Knee. A Randomised, Placebo-controlled, Double-blind Study.

Article Summary:
Glucosamine sulfate has been demonstrated to be effective for treating arthritis when administered in the oral form. This study used glucosamine sulfate in intramuscular administration for 4 weeks to treat osteoarthritis. One group in the study was given a placebo instead of the glucosamine. The patients reported pain on the Lequesne index, and the osteoarthritis was examined to determine the effect of the injected glucosamine sulfate. The injected glucosamine sulfate was more effective than the placebo at reducing pain and alleviating some of the arthritis.

Reichelt A. Forster KK. Fischer M. Rovati LC. Setnikar I.

University Clinic of Orthopedics, Freiburg/Brsg. Fed. Rep. of Germany.

Country of Publication:

Arzneimittel-Forschung. 44(1):75-80, 1994 Jan.

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