Glucosamine Decreases Progression of Knee Osteoarthritis

Glucosamine Significantly Reduces Knee Osteoarthritis

Glucosamine Sulfate Significantly Reduces Progression Of Knee Osteoarthritis Over 3 Years: A Large, Randomised, Placebo-Controlled, Double-Blind, Prospective Trial.

Article Summary:
This study examined the use of glucosamine sulfate as a treatment for osteoarthritis over an extended period of 3 years. Participants were divided into two groups, one who received a placebo, and the other who received the 1500mg glucosamine sulfate daily. Feelings of pain associated with the osteoarthritis were measured, along with the joint space width of the joint involved in the osteoarthritis. Those who continued on the placebo treatment had continued joint space narrowing, while those taking the glucosamine sulfate had very little to no joint space narrowing over the 3 year period. Glucosamine sulfate is considered a safe, long term treatment for osteoarthritis that is capable of stopping the degenerative effects of arthritis.

J Y Reginster, R Deroisy, I Paul, R L Lee, Y Henrotin, G Giacovelli, J Dacre, L C Rovati, C Gosset.

Disclosure: Work reported in this abstract was supported by the Rotta Research Group

American College of Rheumatology 1999 Annual Meeting, Boston, MA Presentation Date: Wednesday, November 17, 1999 Arthritis & Rheumatism 1999;42(suppl)

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